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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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Recombinant mouse CCL4 (C-C motif chemokine ligand 4) is a proinflammatory chemokine expressed in E. coli and supplied lyophilized for research use. It promotes leukocyte chemotaxis, acts as a monokine that can form homodimers, and is provided with high purity suitable for in vitro studies of inflammation and immune cell migration.
High purity (>95%) as determined by reducing SDS-PAGE.
Recombinant expression in E. coli without affinity tag.
Supplied lyophilized from buffered formulation for stability.
Predicted molecular mass ~7.8 kDa (observed ~5-10 kDa by SDS-PAGE).
Intended for in vitro research applications studying chemotaxis and inflammation.
Stable when aliquoted and stored at -20°C or -80°C for extended storage.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3 and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
Orally active TRPV4 antagonist.
Excellent selectivity for related TRP receptors (TRPV1, TRPV3, TRPM8).
TRPV4 probe for focus screens.
IC50s: 0.26 μM for hTRPV4, 0.39 μM for rTRPV4.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Aryl Hydrocarbon Receptor Antibody (YA610) is a rabbit-derived, non-conjugated IgG monoclonal antibody. It targets the Aryl Hydrocarbon Receptor and is protein A affinity purified. This antibody is for research use only.
Rabbit-derived
IgG monoclonal antibody
Targets Aryl Hydrocarbon Receptor
Protein A affinity purified
Non-conjugated
Reactive with human samples
Suitable for Western Blot (WB) and Immunocytochemistry/Immunofluorescence (ICC/IF) applications
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(7S)-BAY-593 is the S-enantiomer of BAY-593, an orally active GGTase-I inhibitor. It effectively blocks YAP1/TAZ signaling in animals and demonstrates significant antitumor activity.
S-enantiomer of BAY-593
Orally active GGTase-I inhibitor
Blocks YAP1/TAZ signaling
Exhibits antitumor activity
Targets YAP/TAZ-TEAD and GGTase I
Soluble in DMSO
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More